Basis
Basis
NAD+ Supplement for Cellular Aging
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Basis
DESCRIPTION
Target aging at the source—your cells. Increase your NAD+ levels with Basis for healthy aging, to boost cellular energy, and maintain healthy DNA. Developed by Elysium chief scientist and renowned aging researcher Leonard Guarente, Ph.D. Increase and sustain NAD+ levels by 40% to:
- Promote healthy aging, feel good for your age
- Promote cellular energy and reduce general tiredness and fatigue
- Fight aging at the cellular level and protect your DNA from stressors
- Support collagen and ceramide synthesis for healthy skin
- Support healthy muscle function
NAD+ Levels and Healthy Aging go Hand-in-Hand
Research published in Nature Aging “suggests that a clear association exists between NAD+ and health status in human aging.” NAD+ (nicotinamide adenine dinucleotide) is found in every cell in your body. It is essential to the chemistry that keeps you up and running.
Unfortunately, NAD+ levels decline universally as we age.
How can you increase your NAD+ levels?
Basis is theevidence-based choice
We now have a way to safely and sustainably boost NAD+levels. Developed by Dr. Leonard Guarente, a leader in thefield of aging research, Basis was clinically proven toincrease NAD+ levels by an average of 40% in a double-blind, randomized, placebo-controlled clinical tria lpublished in the peer-reviewed journal Nature Partner Journals: Aging and Mechanisms of Disease.
Boosted NAD+ activates sirtuins, supports cellular energy and metabolism, targets cellular aging to promote a healthy cellular aging process, and helps maintain healthy DNA.
"I believe Basis is a product that can improve
cellular health and target, at least, some of thedeficits incurred by aging. It is an important partof a strategy that I follow, along with exerciseand a healthy diet, to maintain an active life as I
enter my seventies, and hopefully much longer."
Leonard Guarente, Ph.D.,Elysium Co-founder and Chief Scientist
INGREDIENTS
Vegetarian, vegan, gluten-free, nut-free, and contains no artificial colors or flavors.
Basis contains two powerful ingredients to combat cellular aging.
Nicotinamide Riboside Chloride (NR)
NR is a naturally occurring form of vitamin B3 and a highly efficient precursor to NAD+—the raw material that the body uses to make NAD+ via a two-step process. This precursor has been shown to preferentially elevate NAD+ compared to nicotinic acid and nicotinamide, also called niacin.
Pterostilbene (PT)
A powerful polyphenol naturally produced by plants to protect against internal and external stress. The potent combination of NR and pterostilbene in Basis is designed to increase NAD+ levels and counter the decrease in the activity of sirtuins, which occurs with normal aging.
Why is Basis unique among NAD+ supplements?
Basis is clinically proven to safely and sustainably increase NAD+ by an average of 40%in humans. Elysium's toxicology study also confirmed the superiority of the NR-E in Basis when compared to the published safety profilesof other NAD+ supplements, underscoring the company's rigorous commitment to research and quality.
The synergistic combination of Elysium'sproprietary and high-purity nicotinamide riboside (NR-E) with potent antioxidant pterostilbene (PT) makes Basis extraordinarily effective. Basis is also third-party tested by independent labs both during and after manufacture for purity and quality, and is independently verified as NSF Certified for Sport.
Hour 4
You just took Basis-nothing could be happening yet, right? Actually, the nicotinamide riboside isalready making big moves. It enters your cells via equilibrative nucleoside transporters, membrane proteins that shuttle molecules across.
*Individual results may vary. This timeline may differ from the typical purchaser's experience and is not intended to represent or guarantee that anyone will receive the same or similar results.
Day 01
NAD+ levels are already on the rise at the cellular level. You can expect support for increased cellularenergy, improved mitochondrial function, housekeeping for your proteome and genome, and cellular
protection from everyday stressors (for example, oxidative stress). Not bad for a day's work.
Day 14
NAD+ levels continue to rise in your cells and throughout your body. Keep doing what you're doing while Basis works in the background.
Day 30
Now results are really adding up. If you had all the gear for NAD+ analysis from whole-blood lysate,you could see for yourself. (Instead,you can read our scientific paper.) Your cellular NAD+ levels arenow 40% higher than they were on day one, and that's where they'll stay if you keep taking Basis.Where is all this NAD+ going? Studies suggest that NR supplementation increases NAD+ and affects NAD+-related metabolites in multiple tissues at 30 days-including your muscle and brain.
Day 60
You've logged 30 days of elevated and sustained NAD+ levels in your cells and tissues. That's a bigdeal because 330 billion cells turn over each day. Colon epithelial cells, for example, turn over in 3-5days while the upper layer of the skin, or the epidermis, takes roughly 39 days to regenerate. NAD+can help with supporting these processes and tissue health. In your skin, more NAD+ can support theprocess of synthesizing ceramide and collagen. Our first human clinical trial on Basis also showed preliminary evidence for supporting liver health and results from our latest, 6-month, human clinicalstudy (published in Hepatology) confirmed these initial findings in healthy adults with non-alooholio fatty liver.
Day 180
A lot happens in six months. What's changed in your life? With Basis, it's all starting to add up-tosystemic health benefits. Basis is supporting multiple tissues and systems, in a sustained manner. Forexample, one study showed that six months of increased NAD+ levels reduced transepidermal waterloss-a measure of overall skin health and barrier function.
Day 365
Congratulations on your first year. NAD+ declines by as much as 50% every 20 years, according to research. But human studies are beginning to show an association between NAD+ abundance andhealthy aging status. Keep taking Basis to counteract the age-related decline of NAD+ and to build on a year's worth of benefits. Just like with exercise, sleep, and diet-consistency is key.
WHO IS BASIS FOR?
01｜PEOPLE FOCUSED ON HEALTHY AGING
01｜PEOPLE FOCUSED ON HEALTHY AGING
As we age, NAD+ levels naturally decline. Basis is designed to support healthy aging at the cellular level, making it suitable for adults who want to take a proactive approach to long-term health and support healthy function as they age.
02｜PEOPLE LOOKING TO MAINTAIN DAILY ENERGY & VITALITY
02｜PEOPLE LOOKING TO MAINTAIN DAILY ENERGY & VITALITY
NAD+ plays an important role in cellular energy processes. Basis is designed to support cellular energy and help maintain everyday vitality, making it a fit for healthy adults with busy schedules who want to support their daily energy levels.
03｜PEOPLE WHO PRIORITIZE CELLULAR HEALTH & LONG-TERM WELL-BEING
03｜PEOPLE WHO PRIORITIZE CELLULAR HEALTH & LONG-TERM WELL-BEING
For those looking beyond how they feel today and focusing on long-term cellular health, Basis offers a targeted approach. Its key ingredients, NR and pterostilbene, are formulated to support NAD+ levels and cellular health.
04｜PEOPLE FOCUSED ON SKIN & PHYSICAL FUNCTION
04｜PEOPLE FOCUSED ON SKIN & PHYSICAL FUNCTION
NAD+ is involved in processes related to collagen and ceramide production, while Basis is also designed to support healthy muscle function. It may appeal to adults who care about maintaining healthy skin, skin barrier function, and physical performance as they age.
05｜MIDDLE-AGED & MATURE ADULTS WITH A LONG-TERM HEALTH MINDSET
05｜MIDDLE-AGED & MATURE ADULTS WITH A LONG-TERM HEALTH MINDSET
Basis has been studied in healthy adults aged 60–80, with research showing an average increase of approximately 40% in NAD+ levels. For marketing purposes, it can be positioned for adults who are becoming more proactive about aging, daily vitality, and long-term health—without making claims about treating or reversing aging.
RECOMMENDED USE
- Take two capsules in the morning, with or without food.
- Each pouch contains a 30-day supply.
- This product is only intended for healthy adults. Do not take if you are pregnant or nursing. Consult with your physician before using.
Our Team
The Elysium team is made up of individuals who are passionate about creating a fundamentally new approach to healthcare, one that focuses not exclusively on disease but on health.
We tackle challenges with creativity, integrity, and a willingness to collaborate. We believe that aging is not only the greatest risk factor for all major chronic conditions, but that aging research represents the most significant opportunity to improve human health today. It is our responsibility to share the benefits of aging research with as many people as possible, to effect real and meaningful change. This includes our colleagues, our families, and our friends—who were the original inspiration for Elysium.
Frequently Asked Questions
Why are sirtuins important for aging?
Why are sirtuins important for aging?
Sirtuins are a family of proteins that regulate celular heath Sirtuins play a key role in regulating cellular homeostasis. Homeostasis involves keeping the cel linbalance. However, sirtuins can only function in the presence of NAD+, nicotinamide adenine dinucleotide, a coenzyme found in alliving cells.
What is Nicotinamide Adenine Dinucleotide (NAD+) and why is it important?
What is Nicotinamide Adenine Dinucleotide (NAD+) and why is it important?
NADt, or nicotinamide adenine dinuceotide is a critical coenzymeound in every cellin your body, and it's invoIved in hundreds of metabolie processes bu NAD.evel decline with age. NADt has two general sets of reactionsin the human body Helping urn nutrients into cellular enery as a key player in metaboliem andworking as a helper molecule for proteins that regulate other cellular functions. These processes are incredibly important.
What is Nicotinamide Riboside (NR) and why is it important?
What is Nicotinamide Riboside (NR) and why is it important?
This form of Vitamin B coud be the key to increasing NAD levels heres why. Nicotinamide riboside is often called NR forshort, and its a precursor to NADt.
meaning i's the raw material from which your body makes NAD+ througha series of chemicaltransformations. Human olinicoalstudies, including ours, have shown
efficacy of NR supplementation in increasing NAD+ levels.
What is Pterostilbene and why is it important?
What is Pterostilbene and why is it important?
Prerostibene is a polyphenol,a type of molecule that occursin plants, particularly smalberries and nuts. Blueberries are a particularly rich source of pterostilbene;
although it is found in grapes, pterostilbene (unlike its cousin resveratrol) doesn't survive the wine-making process.
What's a polyphenol?
What's a polyphenol?
'Phenol" refersto a certain chemicalstructure (in this case, a hydroxyl group linked to a benzene ring), "poly"just means the molecules have more than one of the
structure. One of polyphenols' main jobs isto help the plant fight offpathogens. When ceaten by humans, polyphenols may serve as powerful antioxidants.
Is there anything I should notice once I start taking Basis?
Is there anything I should notice once I start taking Basis?
Rasis is designed to work beneath the surface. to its primary purpose is not to deliver surface level results, Taking Basis is an investment in the long term health of
your cells, and you may not fe different despite the improvements happening inside your body.Everyone's plysiology is unique and results vary from person to
person.